ABSTRACT
Darier’s disease is characterized by dense keratotic lesions in the seborrheic areas of the body such as scalp, forehead, nasolabial folds, trunk and inguinal region. It is a rare genodermatosis, an autosomal dominant inherited disease that may be associated with neuropsichiatric disorders. It is caused by ATPA2 gene mutation, presenting cutaneous and dermatologic expressions. Psychiatric symptoms are depression, suicidal attempts, and bipolar affective disorder. We report a case of Darier’s disease in a 48-year-old female patient presenting severe cutaneous and psychiatric manifestations.
.Subject(s)
Female , Humans , Middle Aged , Bipolar Disorder , Darier Disease/pathology , Skin/pathology , Bipolar Disorder/genetics , Darier Disease/genetics , Mutation , Severity of Illness IndexABSTRACT
Subject(s)
Child , Female , Humans , Hair Diseases/pathology , Hair Diseases/physiopathology , Hair/pathology , Microscopy, Polarization , Nervous System Diseases/physiopathologyABSTRACT
Trichilemmoma is a benign neoplasm from the outer sheath of the pilosebaceous follicle. Desmoplastic trichilemmoma, a rare variant, is histologically characterized by a central area of desmoplasia that can clinically mimic an invasive carcinoma, requiring histopathological examination to define the diagnosis.
Subject(s)
Aged , Humans , Male , Carcinoma/pathology , Hair Diseases/pathology , Hair Follicle/pathology , Skin Neoplasms/pathology , Diagnosis, Differential , Skin/pathologyABSTRACT
Hansen's disease is a chronic infecto-contagious disease caused by Mycobacterium leprae. The bacillus prefers low-temperature areas and the nose is usually the initial site of lesions. Transmission of the bacilli occurs by nasal and oropharyngeal secretions, and through solutions of continuity of the skin and/or mucosae. Nasal manifestations are found in the later stages of the disease.
Subject(s)
Humans , Male , Aged , Leprosy, Lepromatous/pathology , Nose Deformities, Acquired/pathology , Nose Diseases/pathology , Nose Deformities, Acquired/microbiology , Nose Diseases/microbiology , Mycobacterium lepraeABSTRACT
The yellow nail syndrome is a rare disorder characterized by the classic triad of yellow and dystrophic nails, lymphedema and pleural effusion. We report in this paper a case of yellow nail syndrome, presenting the classic triad of the disease, associated with an unusual lymph accumulation in the abdomen region.
Subject(s)
Humans , Male , Middle Aged , Abdominal Wall/pathology , Yellow Nail Syndrome/pathology , Lymphedema/pathology , Pleural Effusion/pathology , Skin/pathology , Tomography, X-Ray ComputedABSTRACT
Cutis verticis gyrata is characterized by excessive formation of scalp skin. It may be primary (essential and nonessential) or secondary. In the primary essential form it presents only folding skin formation on the scalp, mimicking cerebral gyri, without associated comorbidities. We report a rare case of a 28 year-old male patient with primary essential cutis verticis gyrata.